Endocrine Abstracts

For the past two decades, genetics has been widely explored as a tool for unravelling the pathogenesis of cardio-metabolic disorders. Many risk alleles for type 2 diabetes and hyperglycaemia have been detected in recent years through massive genome-wide association studies and evidence exists that most of these variants influence pancreatic β-cell function. Investigations of more detailed physiological phenotypes, are now emerging and give indications of more specific pat...

Endocrine Connections, 2020, 9(4): 279–288 (DOI: https://doi.org/10.1530/EC-20-0009)...